System Not Yet Approved for Sale in the US or the EU.

Blood Centers

4 veils of plasma being examined by a scientist.

Introduction to FrontlineODP™

FrontlineODP™ Spray Dried Plasma is designed for easy integration into blood center component laboratories. Decentralized production would take advantage of existing deep blood component manufacturing expertise and product supply chains, from established volunteer blood donor bases to end user distribution including emergency logistics channels.
Decentralized production would establish local dry plasma self-sufficiency and availability for national emergency preparedness, including civilian, government and military collaboration for strategic stockpiles and readiness for mass casualty events.
Applications in Industry

The FrontlineODP™ system is designed to be deployed at blood centers that would produce dry plasma for use by hospitals and emergency first responders.

Intended to treat patients suffering from traumatic hemorrhage.

FrontlineODP™ has the potential to reduce the number of hemorrhagic deaths, especially for patients injured in remote or austere settings, over 20 minutes away from trauma centers.

Value & Benefits of FrontlineODP™
Pivotal studies show that early transfusion of plasma improves patient outcomes and prevents unnecessary death from bleeding in military and civilian situations.
Early transfusion with plasma has been shown to save lives in patients with major traumatic hemorrhage.
FrontlineODP™ has a long shelf life and can be reconstituted quickly.
Availability at the point of care increases the potential to achieve a 1:1 pRBC:plasma ratio.
FrontlineODP™ has the potential to overcome storage and thawing logistics of frozen plasma and provide product handling advantages (reduced breakage, frozen storage constraints, and preparation time).

Why is it needed?

FrontlineODP™ aims to enable transfusion closer to the point of injury. It is intended to be deployed in ground and air ambulances, and to extend the availability of plasma transfusion to rural and austere settings.

Velico's® FrontlineODP™ Business Model

Velico's® business model will be based on partnerships with regional blood centers which collect, test and manufacture lifesaving blood components every day. Velico's® FrontlineODP™ system is being designed for straight forward integration into existing blood component manufacturing centers.

The FrontlineODP™ development program is funded by the Biomedical Advanced Research and Development Authority (BARDA), within the Office of the Assistant Secretary for Preparedness and Response in the U.S. Department of Health and Human Services under contract No. 75A50121C00059. 

Rehydrated Plasma

Resulting Plasma

Velico® is developing FrontlineODP™, a novel, platform technology for manufacturing spray dried human plasma. The FrontlineODP™ system is intended to be deployed at regional blood centers that will produce dry plasma for use by hospitals, emergency first responders and the military. Dry plasma overcomes the logistics of conventional frozen plasma and potentially extends the availability of plasma closer to the point of injury, including rural and austere settings. The resulting plasma units are compact and can be stored either refrigerated or at room temperature.


FrontlineODP™ is easily reconstituted with 200 ml of sterile water for injection (SWFI), and ready for use within minutes, making it practical in prehospital settings where conventional plasma is unavailable.


Uncontrolled hemorrhage is recognized as the leading cause of potentially preventable death among victims of trauma.† The early administration of plasma has been shown to be lifesaving for many of these patients.

† Sperry JL, et al. Prehospital Plasma during Air Medical Transport in Trauma Patients at Risk for Hemorrhagic Shock. N Engl J Med. 2018 Jul 26;379(4):315-326

Want to learn more?

If you are a blood center, hospital, investor or interested in learning more about Velico®, please click the button below to submit a request.